Penrith remain unbeaten but they'll be itching to make a statement against the Warriors after blowing a commanding lead to draw with Newcastle last round.
The Panthers may well fit in some extra field goal practice during the week after the unlucky Matt Burton missed five attempts.
Meanwhile, the Warriors are coming off a terrific win over the struggling Dragons in which they completed an astounding 46 of 48 sets - including 44 straight sets - and didn't concede a point.
Match: Panthers v Warriors
Round 4 -
Venue: Campbelltown Stadium, Sydney
Panthers: Billy Burns replaces Liam Martin on the interchange and Charlie Staines also was omitted from the squad on Thursday night. Brent Naden and Jack Hetherington were cut an hour before kick-off. The Panthers have won five of their past seven games against the Warriors.
Warriors: A late change an hour before kick-off with Josh Curran dropping off the interchange bench. Karl Lawton has been switched from the centres to the bench and Hayze Perham will play centre in jersey No.20. Ken Maumalo is out with a hamstring injury and is expected to sideline him for another three weeks, with Adam Pompey to replace him on the wing. Leivaha Pulu also dropped off the extended bench 24 hours before kick-off while Chanel Harris-Tevita was omitted an hour before kick-off. Peta Hiku (ribs) and Agnatius Paasi (suspension) are out. New signing Poasa Faamausili joins the bench. The Warriors have not won at Campbelltown since 2007.
Fullback for Panthers is number 1 Caleb AekinsFullback for Warriors is number 1 Roger Tuivasa-Sheck
Winger for Panthers is number 2 Josh MansourWinger for Warriors is number 2 Patrick Herbert
Centre for Panthers is number 3 Dean WhareCentre for Warriors is number 4 Gerard Beale
Centre for Panthers is number 4 Stephen CrichtonCentre for Warriors is number 20 Hayze Perham
Winger for Panthers is number 5 Brian To'oWinger for Warriors is number 21 Adam Pompey
Five-Eighth for Panthers is number 6 Matt BurtonFive-Eighth for Warriors is number 6 Kodi Nikorima
Halfback for Panthers is number 7 Jarome LuaiHalfback for Warriors is number 7 Blake Green
Prop for Panthers is number 8 James TamouProp for Warriors is number 8 Jamayne Taunoa-Brown
Hooker for Panthers is number 9 Apisai KoroisauHooker for Warriors is number 9 Wayde Egan
Prop for Panthers is number 10 James Fisher-HarrisProp for Warriors is number 10 Adam Blair
2nd Row for Panthers is number 11 Viliame Kikau2nd Row for Warriors is number 11 Eliesa Katoa
2nd Row for Panthers is number 12 Kurt Capewell2nd Row for Warriors is number 12 Tohu Harris
Lock for Panthers is number 13 Isaah YeoLock for Warriors is number 13 Isaiah Papali'i
Interchange for Panthers is number 14 Mitch KennyInterchange for Warriors is number 3 Karl Lawton
Interchange for Panthers is number 15 Zane TetevanoInterchange for Warriors is number 14 Jack Murchie
Interchange for Panthers is number 16 Moses LeotaInterchange for Warriors is number 15 Poasa Faamausili
Interchange for Panthers is number 19 Billy BurnsInterchange for Warriors is number 16 King Vuniyayawa
Isaah Yeo has been enormous for Penrith this season, pumping out huge numbers and minutes in the middle. The opposite No.13, Adam Blair, set the tone against the Dragons, and the Warriors will again look to the veteran for leadership here. Both men can have a big influence on their teams.