Penrith remain unbeaten but they'll be itching to make a statement against the Warriors after blowing a commanding lead to draw with Newcastle last round.
The Panthers may well fit in some extra field goal practice during the week after the unlucky Matt Burton missed five attempts.
Meanwhile, the Warriors are coming off a terrific win over the struggling Dragons in which they completed an astounding 46 of 48 sets - including 44 straight sets - and didn't concede a point.
Panthers: Billy Burns replaces Liam Martin on the interchange and Charlie Staines also was omitted from the squad on Thursday night. Brent Naden and Jack Hetherington were cut an hour before kick-off. The Panthers have won five of their past seven games against the Warriors.
Warriors: A late change an hour before kick-off with Josh Curran dropping off the interchange bench. Karl Lawton has been switched from the centres to the bench and Hayze Perham will play centre in jersey No.20. Ken Maumalo is out with a hamstring injury and is expected to sideline him for another three weeks, with Adam Pompey to replace him on the wing. Leivaha Pulu also dropped off the extended bench 24 hours before kick-off while Chanel Harris-Tevita was omitted an hour before kick-off. Peta Hiku (ribs) and Agnatius Paasi (suspension) are out. New signing Poasa Faamausili joins the bench. The Warriors have not won at Campbelltown since 2007.
Isaah Yeo has been enormous for Penrith this season, pumping out huge numbers and minutes in the middle. The opposite No.13, Adam Blair, set the tone against the Dragons, and the Warriors will again look to the veteran for leadership here. Both men can have a big influence on their teams.