It was a drama-filled round of injuries just three rounds away from the Telstra Premiership finals.
Penrith will be without their Origin series-winning five-eighth James Maloney until the first week of the finals after a set of scans revealed serious knee ligament damage.
The 32-year-old has a grade two medial ligament tear from the win over the Gold Coast, and will now miss the three remaining club rounds against the Knights, the Warriors and Storm.
Roosters prop Jared Waerea-Haregreaves is set to miss up to a month after suffering broken ribs in the Roosters' round 22 win over South Sydney.
Cronulla back-rower Wade Graham underwent two sets of scans on Monday on his right knee. He strained medial ligaments in the win over Melbourne but is only expected to miss just the one week.
It was also good news for Rabbitohs fullback Alex Johnston, who should be available for the Broncos this weekend after scans on his hamstring injury.
Storm veteran Ryan Hoffman suffered a hamstring and may not play again as he's retiring at season's end.
Canberra skipper Jarrod Croker, who dislocated his kneecap in round 17 to end his season, said he will be back in time for a full pre-season with the Raiders.
There is also good news for the Raiders concerning winger Michael Oldfield who said he is an outside chance of playing again before the end of the season despite suffering a serious medial ligament injury.
Here's how the 16 NRL clubs are shaping up on the injury front.
Andre Savelio (knee, season)
Matt Gillett (neck/calf, season)
Payne Haas (shoulder, season)
Jack Bird (sternum, indefinite)
Jaydn Su'A (ankle, season)
Josh McGuire (suspension, round 23)
Jack Wighton (stood down on disciplinary grounds, finals)
Ata Hingano (ankle, season)
Jarrod Croker (knee, season)
Michael Oldfield (knee, season)
Aidan Sezer (hamstring, TBC)
Raymond Faitala-Mariner (knee, season)
Marcelo Montoya (hamstring, season)
Kieran Foran (toe, season)
Lachlan Lewis (family matter, round 23)
Kurt Capewell (thumb, round 24)
Jack Williams (pectoral, season)
Edrick Lee (shoulder, round 24)
Wade Graham (knee, round 24)
Luke Lewis (leg, TBC)
Gold Coast Titans
Max King (shoulder, season)
Dale Copley (hamstring, season)
Brenko Lee (hamstring, round 23)
Tyronne Roberts-Davis (neck, season)
Morgan Boyle (shoulder, season)
Michael Gordon (wrist, indefinite)
Manly Warringah Sea Eagles
Lachlan Croker (ACL, season)
Curtis Sironen (knee, season)
Apisai Koroisau (foot, round 23-24)
Akuila Uate (ankle, season)
Martin Taupau (leg, round 23)
Brian Kelly (leg, round 23)
Sam Kasiano (knee, round 23-24)
Ryan Hoffman (hamstring, TBC)
Jacob Saifiti (shoulder, indefinite)
Tautau Moga (knee, season)
Slade Griffin (knee, season)
Nathan Ross (groin, indefinite)
Jacob Lillyman (abdominal, round 23-24)
Connor Watson (groin, round 24)
North Queensland Cowboys.
Michael Morgan (biceps, season)
Josh Chudleigh (knee, season)
Sam Hoare (knee, season)
Antonio Winterstein (knee, retired)
Shaun Fensom (concussion, round 23)
Tony Williams (knee, season)
Beau Scott (knee, retired)
Manu Ma'u (cheekbone/eye socket, season)
Cameron King (knee, round 24)
Daniel Alvaro (knee, round 24)
Kaysa Pritchard (shoulder, season)
Kirisome Auva'a (foot, round 23)
Jarome Luai (ankle, season)
Peter Wallace (shoulder, retired)
Dylan Edwards (shoulder, season)
Tim Browne (bowel, retired)
Sam McKendry (knee, season)
James Tamou (cork/ankle, round 23)
James Maloney (knee, finals)
South Sydney Rabbitohs
Greg Inglis (thumb, round 23)
Adam Doueihi (knee, season)
Robert Jennings (hamstring, finals week 1)
Alex Johnston (hamstring, round 23-24)
Mark Nicholls (fractured fibula, indefinite)
Zane Musgrove (foot, round 24)
St George Illawarra Dragons
Jacob Host (shoulder, round 23-24)
Nene Macdonald (foot, round 23)
Paul Vaughan (ankle, round 25-finals week 1)
Gareth Widdop (shoulder, round 25-finals)
Jared Waerea-Haregreaves is set to miss up to a month after suffering broken ribs in the Roosters' round 22 win over South Sydney.
Luke Keary (knee, round 25)
Jared Waerea-Hargreaves (ribs, finals)
Nathaniel Roache (neck, season)
Tohu Harris (knee, round 24-25)
Sam Lisone (suspension, round 24)
Corey Thompson (ankle, season)
Josh Reynolds (shoulder, season)
Mahe Fonua (broken arm, round 23)
Chris Lawrence (hamstring, broken hand, round 23)
Josh Aloiai (broken hand, round 24)
Tim Grant (knee, round 23)