In his 68 minutes on the field, Lowrie made 41 tackles only hooker Nathan Friend (44) made more on a night when the Vodafone Warriors were forced into heavy defensive duty as Penrith handed them a club record 62-6 loss.
Following todays medical review, Lowrie faces two to three weeks out of action.
If he recovers quickly he could be ready for the Monday night encounter with Brisbane at Suncorp Stadium on June 3; if not his first game back shapes as being the 13th-round match against Manly at Mount Smart Stadium on Sunday, June 9.
The Vodafone Warriors updated injury list (anticipated return date in brackets) is:
Todd Lowrie - Ribs (Round 13)
Jerome Ropati - Hamstring (Round 11)
Kevin Locke - Back (Round 11)
Dane Nielsen - Ribs (Round 11)
Sam Lousi - Foot (Round 12)
Sio Siua Taukeiaho - Leg (Round 14)
Steve Rapira - Knee (out for season)
Sione Lousi - Knee (out for season)